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She even lowered her Body Mass Index (BMI) 10 pointsfrom 34.1 to 24.2

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In fact, a 2008 study found that after taking a 1,000 mcg oral supplement, only approximately 1.3% (or 13 mcg) of B12 was absorbed into the bloodstream

Reader beware, this is a complex topic, but nonetheless, lets dig into this a bit more, with a look at how MTHFR relates to DNA methylation and the one-carbon pathway